ANTVIRAL ACTIVITY OF JASMINUM SAMBAC (L.) AITON AGAINST FOOT AND MOUTH DISEASE VIRUS

نویسندگان

چکیده


 Jasminum sambac (L.) Aiton, a plant used in this study to exploit its virucidal as well cytoxic potential against Foot and Mouth Disease Virus (FMDV) by using cell culture technique. FMD virus considered causal agent of the disease which influences domesticated livestock became cause intense sickness. Analysis was done with help extract that collected from stem leaf plant. Extract taken different solvents such n-hexane, chloroform aqueous extract. Results analysis revealed n-hexane did not have any ability Food cells Baby Hamster Kidney (BHK-21) non-toxic at concentration range 3.9 μg/mL-250 μg/mL while alcohol showed antiviral 1000 μg/mL-2000 range. Meanwhile, toxic 2000 BHK-21 125 250 μg/mL. Aqueous Cell Survival Percentage (CSP) fifty two percent (52%) their ability, both extracts confirmed toxicity Aiton is due oleuropein, chemical constituent, constituent flowers inhibits efficiently excretion Hepatitis B surface antigen (HBsAg) human hepatic (HepG2).

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ژورنال

عنوان ژورنال: Pakistan journal of science

سال: 2022

ISSN: ['0030-9877', '2411-0930']

DOI: https://doi.org/10.57041/pjs.v73i4.390